http://www.stormsupplements.com/gaba-gamma/

Sublingual or Intranasal administration of Gamma Aminobutyric Acid (GABA) Does it by/pass the Central NervousS
No. GABA does not cross the blood brain barrier to any appreciable extent. In re-reading your question, maybe that’s not what you are asking. Does it bypass the CNS? Not sure what you mean.
GABA (Gamma Amino Butyric Acid)