S-Farnesylated Cysteine Peptides DefinitionRAS and many other oncogenic proteins undergo a complex series of post-translational modifications that are initiated by the addition of farnesyl or a geranyl-geranyl moiety to C-terminal cysteine(s) of the target protein through a process known as prenylation. DiscoveryFujiyama A in 1991 demonstrate that polyisoprenylation and methyl esterification of the cysteine residue [...]
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